
Professor Costa’s groep heeft een bijzonder boeiende studie gedaan, waaruit blijkt dat PEA meer is dan een natuurlijke pijnstiller alleen. PEA heeft ook een intrinsiek positief effect op de diabetes, door de cellen van de alvleesklier te beschermen en door de aan insuline gerelateerde functie van de pancreas te ondersteunen.
We explored the ability of PEA to also relief this kind of chronic pain, employing the well-established streptozotocin-induced animal model of type 1 diabetes.Our findings demonstrated that PEA relieves mechanical allodynia, counteracts nerve growth factor deficit, improves insulin level, preserves Langherans islet morphology reducing the development of insulitis in diabetic mice.
These results suggest that PEA could be effective in type1 -diabetic patients not only as pain reliever but also in controlling the development of pathology.
Bron(nen) : Internet
Donvito G, Bettoni I, Comelli F, Colombo A, Costa B. Palmitoylethanolamide relieves pain an2d preserves pancreatic islet cells in a murine model of diabetes. CNS Neurol Disord Drug Targets. 2015 Apr 29.
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